A brief history of mammalian cell culture
Primary and continuous cultures
Methods in mammalian cell culture
Applications of cell culture in virus production
Concepts of Energy Production and Conservation
General Principles of Risk Assessment
Food and Feed as, or Derived from, Transgenic Crops
Levels of information processing
Traditional information support in biosciences: bibliographic databases
Value added processing of databases
Nucleic Acid Research and Genomics
Protein Research and Proteomics
Biotechnology of Traditional Fermented Foods and Beverages
Biotechnological Processes Produced Under Conditions of Sterility
Applied Genetics and Genetic Engineering – Their Influence on Biotechnology
Methods in biotechnology: A topic in its own right
When methods are used in biotechnology
Identifying the need for a method, finding, choosing, using and reporting methods in biotechnology
Methods in biotechnology – current state and future prospects
Common Instruments for Process Automation
Advanced Instrumentation for Bioprocess Control and Automation
Methods for Protein Determination
Methods for the Determination of Carbohydrates
Methods for Determination of Lipids
The Characterization of Potential Feedstocks in Sugar Cane
Physical Methods used for the Characterization of Lignocellulosic Materials
Bioprocesses Based on Sucrose Consumption such as in Sugar Cane Juice
Bioprocesses Based on Lignocellulosics such as Sugar Cane Bagasse
What Can Mathematical Models Do for Biotechnological Processes?
Overview and General Principles of Mathematical Modeling Biotechnological Processes
Case Study 2: Mathematical Model of a Differential Reactor for Estimating Kinetic Constants
Molecular Biotechnology Approaches Applied to Livestock Systems
Gene Engineering with Polymerase Chain Reaction
Genetic manipulation in bacteria
Introduction of DNA into bacteria
Polymerase chain reaction (PCR)
Expression and protein purification
Genetic manipulation of bacteria
Generation of transforming constructs
Principles of Microalga Culture
Genetical Identification and Phylogeny
Genetic Engineering of Algae: Examples of Environmental and Industrial Applications
Transformation of dicotyledonous plants
Transformation of monocotyledonous plants
Expression and Regulation of Eukaryotic Genes
Strategies for Protein Engineering
Cost-effective and sustained production of nutritious food
Why do we have GMO regulations?
Extremophiles and biomolecules
Extremophile genomics exposing the biotechnological potential
Tapping into the hidden biotechnological potential through metagenomics
Characteristics of Genetic Information: The Claim of Genetic Exceptionalism
Roots of Modern Biocalorimetry
Information Content of Calorimetric Signals
Localization of Calorimetric Sensors
Recent Developments of Calorimetry
Future Prospect of Biocalorimetry
Bioreactors with Mechanically Moved Internal Part
Bioreactors with a Circulation Pump
Bioreactors Mixed by Compressed Gas Sparging
The Large-Scale Pneumatic Bioreactors
Sterilization of Small Equipment
General Aspects of Foam Fractionation
Foam Fractionation of Proteins
The Drug Discovery and Development Process
Optimization of Chemical Structure
Optimization of the Growth Medium
Optimization of the Operating Environment using Process Control
Application to Bioreaction Modeling
Modes of Operation in Fermentation
Steps of a Control System Design: The Biotechnologist’s Role
Biodegradative Pathways for Biotransformations
General Theoretical Background of Plant Cell and Tissue Cultures and Their Processes
Description of Most commonly used Types of Plant Cell Bioreactors
The P. Pastoris Expression System
Bioreactor Process Techniques for Production of Recombinant Proteins with P. Pastoris
From Bioprocess Selection to Bioreactor Design and Operation
CO2 in Biotechnological Fermentation Processes
CO2 as A Carbon Feedstock for Biofuels Production
CO2 as A Feedstock in Bio-Based Polymer Synthesis
CO2 as A Feedstock in Syntheses of Other Natural Products
Enhancing Effect of CO2 on Secreted Enzyme Production
Influence of CO2 on Microbial Growth
CO2 measurement in biotechnological fermentation processes
Calculation of Dissolved Carbon Dioxide Concentration from Exhaust Gas Analysis
Good Manufacturing Practice (GMP)
Alcoholic Beverages from miscellaneous substrates
b-lactam Antibiotics as a Model System
Penicillin, Cephalosporin and Cephamycin Biosynthesis: An Overview
Regulation of Penicillin Biosynthesis
Clustering of Genes for the Biosynthesis of b -lactam Antibiotics
The first step: Selection of an expression system
Production of Bacillus Thuringiensis and Bacillus Sphaericus
Entomopathogenic Protozoa and Microsporida
Diversity and potential of plant cell culture
Regulation of production through elicitation and induction
Preliminary economics of using plant cell culture for secondary metabolite production
Limitations/opportunities for marketing plant cell culture products
Development of the Industrial ABE Fermentation Process
The Commercial ABE Fermentation Process
Limitations of the Industrial ABE Fermentation Process
Advances in Scientific Know-how
Advances in Process Technology
Future development and challenges
Lignocellulosic biomass of Livestock Excreta
Multiproduct formation from biomass crops(Recycling) of Livestock Excreta
Product formation from human, animal and agricultural wastes
Cytotoxic, Antitumour and Antineoplastic Metabolites
Symbiosis and Bioactive Metabolites
Traditional and current bio/technology using acetic acid bacteriaHydrocarbons
Acetic acid bacteria as spoilers
Technological solutions in bio/technology using acetic acid bacteria
Biomass as a source of food or fuel? What are the issues?
Net primary productivity (NPP)
Biomass as food/fuel and recycling
Models for small-farm scale production of feed/food and energy
Priorities of Waste Management and Resource Recovery
Secondary Recycling via Thermal Recovery
Optimal Thermo-Biorefinery Campus Design
The First Generation of Biofuels
The Second Generation of Biofuels: "Cellulosic Ethanol"
Renewable Esters: The Next Generation of Hybrid Biofuels
The Mini-Biofuels Refinery Technologies
Status/Business Strategy/Competitive Advantages/Market Opportunity
A General Discussion of the Superior Fuel Traits of Bio-butanol
The Old World War II ABE Fermentation
What is a genome, and why map it?
Putting it all together -- a case study of the sorghum genome
Biological Catalysts for Hydrogen Production
Definitions: Probiotic, Prebiotics, Synbiotic and Integrated Synbiotics
Commercial Impact of Probiotic Products
Requirements for Probiotic Microorganisms and Probiotic Food
Health Benefits of Probiotic Microorganisms
Increasing the Effectivity of Probiotics by Chemical and Biological Encapsulation
Manufacturing of Probiotics and Products with Probiotic Properties
Application Strategies in the Utilization of Probiotic Strains
Improving Shelf Life of Probiotics
Microbial inoculation of plants
Fermentation and enzyme technology
Transformation of plants and animals
Crop protection through pest resistance genes
Livestock-based biotechnologies
The economics of agro-biotechnology
Fermented foods from vegetables
Fermentations for the Production of Coffee, Tea and Cocoa
Crop Requirements for Nitrogen
Potential for Biological Nitrogen Fixation [BNF] SystemsMushrooms
The Biochemistry of Biological Nitrogen Fixation: The Nitrogenase System
The Genetics of Nitrogen Fixation
The Potential for Biological Nitrogen Fixation with Non-legumes
An Outline of the Composting Operation
Herbicide and Disease-Resistant Crops
Manufacturing Proteins in Plants
Nutritional Enhancement of Plants (Nutriceuticals)
Methods for Producing Transgenic Animals as Bioreactors
Control of Transgene Expression in Transgenic Animal Bioreactors
Biotechnology in Plant Breeding
Products of Crop Genetic Engineering
Potential Consequences of Crop Biotechnology and Genetic Engineering
Technical aspects of agricultural biotechnology at the interface with agrobiodiversity
Agro-biodiversity as a source for biotechnological applications
Important Economic Aspects of Agrobiotechnology
Methodological Approaches to Assess the Benefits and Costs of Agrobiotechnology
Macro-Evolution and Micro-Evolution
The Worldwide Redistribution of Plants
Stable and Unstable Protection Mechanisms
Quantitative and Qualitative Genetics
Quantitative (Horizontal) and Qualitative (Vertical) Resistance
The Gene-for-Gene Relationship
Vertical Resistance and Horizontal Resistance Compared
Special Aspects of Horizontal Resistance
Genetic Engineering Technologies
Insect resistant vegetable crops
Virus-resistant vegetable crops
Why Plant Genetic Resources (PGR) Are Important to Farmers
How Farmers Manage and Use Plant Genetic Resources
Advancing PGR with Farmers: Joining Formal and Informal Research
Understanding the 'plant genome’
Arabidopsis Genome Sequence -The signpost of plant genomics
Industries Based on Marine Biotechnology
Scientific Studies with a Commercial Potential
Role of Microbial Enzymes in Marine Environment
Enzymes from Marine Microorganisms
Enzymes as Tools in Biotechnology
Microbial Disease Problems in Aquaculture
Bacterial Pathogens Associated with Seafoods
Biotechnological Tools in Safety Assurance
Antibiotic Resistant Bacteria in Aquatic Systems and Monitoring their Presence by Molecular Methods
The Importance of Biodiversity Research in the Marine Environment
What Questions can be Answered Using Molecular Biology Techniques?
Evaluating Marine Biodiversity by Sequence Analysis and Fingerprinting Methods
Analysis of Population Structure Using Molecular Markers
Molecular Probes for Identification and Characterisation of Marine Phytoplankton
Cultivation of Extremophilic Archaea
Molecular Basis of Heat Resistance
Screening Strategies for the Detection of Novel Enzymes from Archaea
Cellulose and Hemicellulose Hydrolyzing Enzymes
History of the Viable but Nonculturable Phenomenon in Bacteria
Rationale of Integrated Aquaculture and Mariculture
Successful Models in New Stages
Eight New Concepts or Trends of Integrated Aquaculture and Mariculture
Livestock Excreta as Livestock Feed
Potential Benefits from the Recycling of Livestock Excreta
Methods of Processing (Recycling) of Livestock Excreta
Excreta as Source of Nutrients for Water Plants, Terrestrial Crops and Earthworms
Key Reactions of Microbially Mediated Degradation of Organics
Modes of Microbially Mediated Detoxification of Organics
Approaches to Increasing Efficiency and Velocity of Detoxification of Organics
Introduction: General Features of the Microbial Degradation of Xenobiotics
The Origins and Evolution of Aquaculture
Sustainable Aquaculture Practices
Dynamics of Intensive Culture Ponds
Harvesting Plankton to Recycle Nutrients and Improve Sustainability
Energy Production Using Anaerobic Digestion Technology
Loss of biodiversity and conservation
Applications of biotechnology and its effect on biodiversity
Microbial Resources: "quoi de neuf ?" (What is new ?)
Microbial Resource Management (MRM)
Exciting new potentials of MRM in Relation to the Super Challenges
Necessity to develop a vermiculture industry
Status of the vermiculture industry
Blood Composition and Functions
Blood Transfusion - Safety and Transmission of Diseases
Red Cell Indices and Morphology in Disease Diagnosis
The Context: The BRCA-Controversy
Conventional Compulsory License
Classes of fungi that are of Medical Interest
Clinical groupings of fungal infections
Miscellaneous fungal or fungal-like diseases
Identification of fungi- The Classical Approach to Fungal Identification
Lysine Biosynthesis Pathway in Bacteria
Identification and validation of targets
Dihydrodipicolinate Synthase (DHDPS)
Routine Antibody Based Methods in Pathology
Novel Protein Investigation Techniques
The Scope of Medical Biochemistry
The Changing Scope of Clinical Biochemistry
Natural History of a Scientific Field
History of Biochemistry and Medical Biochemistry
The Emergence and Evolution of Clinical Biochemistry
Methodology: the Principal Driver of Developments in Clinical Biochemistry
Scientific Infrastructure of Medical and Clinical Biochemistry
Academic Contribution of Clinical Biochemistry
Clinical Biochemistry or Laboratory Medicine?
Structure and Function of Enzymes
Abzymes - A Challenge for Medical Biotechnology
Perspectives for Abzyme Technology As A New Branch Of Medical And Pharmaceutical Biotechnology
Introduction: The Concept Of Medicinal Plants And Phytobiotechnology
A Recap of Infectiology and Contemporary Challenges in the Control of Infectious Diseases
Medicinal Plants and Macrofungi in Control of Fungal Infections and Other Dermatological Problems
Employing Appropriate Medicinal Plant Biotechnology in the Management of HIV/AIDS And Cancer
The Micro- and Nanoscale Structure of the Central Nervous System (CNS)
Synthetic and Engineering Methods in Nanotechnology
Applications of Nanoengineering and Nanotechnology to the CNS
Challenges Associated with Nanotechnology Applications to the CNS
TP53 Mutations and Human Cancer
The p53 Protein—A Sensor of Genotoxic Stress
The p53 Pathway as a Target for Pharmacological Intervention
Strategies to Generate Transgenic Mice
Nanotechnology and Nanomedicine
General Aspects of Xenobiotic Metabolism
Methods for Studying in vitro Metabolism
Determination of Metabolism in in vitro Systems
Basic requirements for a State-of-the-Art Biopharmaceutical Development Facility
General considerations for a multi-process/multi-product biotech manufacturing facility
Restrictions on use of gene and research tool patents
Increasing complexity of the patent landscape
Social policy considerations in the healthcare arena
Social policy considerations in the public sector research arena
Foreign Body Implants / Tissue Fillers
Types of Biobanks: Population Banks vs. Disease Specific Banks
Commercialization of Genetic Data: Common Heritage of Humanity vs. Private Interests?
Public Involvement: Can or Should Researchers and Participants be Partners?
Ethical evaluation: The Belgian (federal) Council on Bioethics
Biotechniques in Bioweaponeering
HPV and cervical cancer development
HPV-mediated transformation: additive events
Deregulation of E6 and E7 transcription
E6 and E7, the viral oncogenes
Epigenetic alterations in cervical cancer
Concept of multistep process of HPV-mediated carcinogenesis and future perspectives
Biotechnology and Genetically Modified Crops
Biotechnology and its Impact on the Public Understanding of Science
Biotechnology and the Ethics of Gene Therapy, Animal Cloning and Gene Manipulation in Humans
The Developing Country Identity
Analyzing the Impact of Biotechnology
Methodological Approaches and Competing Discourses
The diplomacy model and environmental discourses
Challenges for the Biotechnology Industry
Reasons for the Lack of Public Acceptance
Some theoretical considerations regarding public confidence
Public Policy Issues related to Biotechnology
Some Reflections on Future Public Policy Towards Biotechnology
Intellectual Property Protection
Moral Arguments Supporting Patenting
Ethical Arguments Against Patenting
Process versus product regulation and the risks of GMOs
Regulating the Laboratory Use of GMOs
Teaching the Basic Principles of Biotechnology
Teaching the Skills of Biotechnology
Advanced Biotechnological Achievements Applied in Rural Areas
Conventional Biotechnology as Practiced in Rural Areas
Socioeconomic, Political and Cultural Impacts on Biotechnology
Biotechnology - Ancestral Art and Culture
Zero-Emission Biotechnology and Environmental Art
Microbes and Cultural Heritage
The Dark Side of Biotechnology - Culture and Peace
Cultural Roots of the Concerns
Patterns in Relief: Women's Knowledge and Management of Plant Genetic Resources
Behaviors in Relief: the Practice and Consequences of Gender Bias
Biological/Chemical Warfare Characteristics
Introduction: Attitudes, behaviours and technology for organic waste reuse
Household and community-scale action for treatment and reuse
Technology choice, behavioural change and institutional supports
The Pacific Region and Medicinal Plants
Pacific Island Medicinal Plants and Intellectual Property Rights
Biodiversity trade in the contemporary Pacific
Population Growth and Food Production
Biotechnology Education and Training Centers [BETCEN]
Biological Nitrogen Fixation [BNF] MIRCENs
Nodulation: From the Infection Process to the Functioning of the Nitrogenase
Measurement: Different Methods to Monitor the Nitrogen Fixation
Improvement: Description of Different Approaches Allowing Maximisation of Nitrogen-Fixation
History of DSM with Regard to its Patent Depositary
MIRCEN activities of DSM in these early years
Present Organisation and Status of DSMZ
The OECD initiative on Biological Resource Centres (BRC-Initiative)
International Centre for Chemical Studies – ICCS
